Evidence of the osseointegration (click) prosthesis

Benefits and risks of osseointegration (click) prosthesis

The surgeon Dr. Jan Paul Frölke and rehabilitation physician Dr. Henk van de Meent and their research team from Radboudumc in Nijmegen have been following all patients treated with an osseointegration prosthesis since 2009 in collaboration with other major centers in the world. They not only investigated the advantages of this treatment, but also mapped out the disadvantages and possible complications. Initially it was thought that the implant would lead to infection of the bone and loosening of the implant. Research published in American international scientific journals showed that the risk of loosening is very small in the first 84 patients with an osseointegration prosthesis. In 1 patient the implant became detached and had to be replaced. Follow-up studies were able to confirm this, but more than two-thirds of the people were found to have regular stoma irritation and infections. Especially in people who smoke and in people with a high body weight. However, the stoma complaints were treatable and are often transient. Due to recently developed new surgical techniques, stoma problems are still rare and the complaints are less. Stoma complaints are now mainly seen in the first two years after surgery.

Initially, it was thought that an implant protruding through the skin would lead to infection of the bone and detachment of the implant. This study of the first 84 patients with an osseointegration prosthesis showed that the risk is very small. In 2% the implant detached from the bone and the implant had to be replaced. Stoma irritation and infections do occur, especially in people who smoke and people with a high body weight. The stoma complaints ca be treated in outpatient settings and are often transient. Due to recently developed new surgical techniques to create the stoma, the stoma problems are still rare and the complaints are less.

  • Walking ability and quality of life in subjects with transfemoral amputation: a comparison of osseointegration with socket prostheses at https://pubmed.ncbi.nlm.nih.gov/23774380/
  • Safety of Osseointegrated Implants for Transfemoral Amputees: A Two-Center Prospective Cohort Study at https://pubmed.ncbi.nlm.nih.gov/27252434/
  • Safety and Performance of Bone-Anchored Prostheses in Persons with a Transfemoral Amputation: A 5-Year Follow-up Study at https://pubmed.ncbi.nlm.nih.gov/32769599/

Cost effectiveness

Cost-effectiveness studies by prof L. Frossard from Brisbane, Australia has revealed that after six years an osseointegration prosthesis is more cost effetive compared to the conventional socket prosthesis

  • Cost-effectiveness of bone-anchored prostheses using osseointegrated fixation: Myth or reality? at https://pubmed.ncbi.nlm.nih.gov/29119860/‚Äč