Van lichamelijke beperking naar grenzeloze vrijheid

Osseointegration: From physical disability to limitless freedom

Welcome to AOFE Clinics
Amputee Osseointegration Foundation Europe Clinics
(AOFE Clinics) is an Independent Treatment Centre specialising in amputation medicine.

Our services is reimbursed by your health insurer!

What does AOFE amputee clinic do?

We give our
patients more

and mobility

For patients with a leg amputation who experience problems wearing a socket prosthesis, there is now a method to anchor the prosthesis to the body. Through the skin, the surgeon can insert an orthopaedic implant directly into the bone of the stump. The artificial bone can be connected to this implant using a click system. This technique is called osseointegration, and the prosthesis is therefore called click prosthesis. Doctors use the term osseointegration prosthesis or bone-anchoring prosthesis. The skin opening through which the implant protrudes is called a stoma.

You can contact our amputee clinic for:


Osseointegration is an innovative method of anchoring the prosthesis to the body. Discover the possibilities.

More info

Stoma revision

Some people with a bone-anchored prosthesis develop stoma problems over the years.

More info

Primary amputation

Primary amputations are performed by a highly experienced and dedicated team of specialists at every level.

More info

Stump revision

Are you suffering from your current socket and not eligible for Osseointegration? We will present you with stump revision options.

More info


TMR is a treatment for people with nerve pain after amputation.

More info
Wat is het principe van osseointegratie? - amputee clinic AOFE Clinics in The Netherlands

What is the principle of osseointegration?

The osseointegration prosthesis comes from dentistry. In the 1960s, it was discovered by Swedish scientist Brånemark that bone bonds very well with the surface of a titanium screw. This connection of metal to bone is called osseointegration, and this principle is now used by orthopaedists to apply hip and knee prostheses to the bone on a large scale. Since the 1990s, this osseointegration technique has been further developed for people with an arm or leg amputation. Unlike a hip or knee prosthesis, here the implant protrudes through the skin so that an artificial arm or leg can be clipped onto it. Since 2009, the osseointegration (click) prosthesis has also been used in the Netherlands amputee clinic and is currently experiencing spectacular growth.

Latest news

Keep up to date with news and
developments in our news section

Latest news

10 July, 2024

AOFE guest KorterMaarKrachtig

AOFE Clinics guests at KorterMaarKrachtig on May 25, 2024.

Read more ➔

Do you recognise
these situations:

read the stories
of our patients

sporten met een amputatie - sport with an amputation

Is an osseointegration (click) prosthesis safe?

Yes, this is a safe treatment. Surgeon Dr Jan Paul Frölke and rehabilitation specialist Dr Henk van de Meent, with their research team at Radboudumc Nijmegen, in collaboration with other major centres around the world, have followed all patients they have treated with an osseointegration prosthesis since 2009. They not only studied the benefits of this treatment but also identified the disadvantages and possible complications. Initially, it was thought that the implant would give rise to infection of the bone and loosening of the implant. Research published in US international scientific journals showed in the first 84 patients with an osseointegration prosthesis that the risk of loosening is very small. In 1 patient, the implant loosened and had to be replaced. Follow-up studies could confirm this, but more than two-thirds of people were found to have regular stoma irritation and stoma infections. Particularly in people who smoked and those with high body weight. However, the ostomy symptoms were easily treatable and often transient. Due to recently developed new surgical techniques, stoma problems are now rare and the symptoms are less. Stoma complaints are now seen mostly in the first two years after surgery.

The five

We listen to you and use a
personalised approach

Our care meets the
strictest quality standards

We always work with
experience experts

We will work with you to find the
most appropriate solution

You benefit from
reduced waiting times with us

Dicky de Best ervaringsdeskundige

Do you have any questions or do
you want to sign up?

You can register directly for an intake interview. Do you still have questions? Then look through the frequently asked questions or ask your question to one of our specialists.