Frölke OOT 2025
New scientific research
In addition to treating patients with amputation-related problems, we also conduct important scientific research with the aim of improving the techniques and care provided. Recent articles that have been published internationally:
1. van Vliet-Bockting C, Atallah R, Frölke JP, Leijendekkers R. Optimization of patient selection in persons with a bone-anchored prosthesis: A prospective 24-months follow-up. study.
This study focused on changes in quality of life after a bone-anchored prosthesis treatment. Furthermore, it was also investigated whether it is possible to predict which patients will improve the most or the least after such treatment. It was also examined whether certain factors are predictive of the development of complications. In this way we try to better predict which patients are suitable for the operation, and we also try to better inform the patients during the outpatient consultation. The results of this study show that the quality of life clearly improves after a bone anchored prosthesis treatment. Patients with the following characteristics see the greatest increase in quality of life: 1. Young patients with lower pre-treatment quality of life scores, 2. Patients with amputations due to an accident who had a low activity level before treatment, 3. Patients with amputations due to vascular diseases, a lower prosthesis comfort, combined with a low-moderate activity pattern. The lowest risk of complications was present in young patients with a high level of functioning, while the following combination of factors gave an increased risk of complications: female gender, age, low activity pattern, longer time since the first amputation.
2. Atallah R, Rutjes E, Frölke JP, Leijendekkers R. Safety and performance of contemporary press-fit titanium lower extremity osseointegration implants: A 5-year follow-up study.
This study investigated the survival of the implant 5 years after treatment, also looking for the first time at the effectiveness of treatment in the medium term in patients with a short above-knee amputation or below-knee amputation. It was shown that the survival is equivalent to that in patients with a long above-knee amputation, for which much more data is available. A mean 5-year survival of 94.2% was achieved, in connection with the removal of 5 implants. It should be emphasized that 2 of the 5 implants were removed at the request of the patient due to unexplained pain, and therefore no clear problem was found with the implant. Furthermore, it was confirmed again that serious complications are rare,
